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1

From NASH to HCC: current concepts and future challenges

Anstee, Quentin M., Reeves, Helen L., Kotsiliti, Elena, Govaere, Olivier, Heikenwalder, Mathias

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2019

Language:

english

File:

PDF, 2.37 MB

english, 2019

2

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

Mildner, Alexander, Schmidt, Hauke, Nitsche, Mirko, Merkler, Doron, Hanisch, Uwe-Karsten, Mack, Matthias, Heikenwalder, Mathias, Brück, Wolfgang, Priller, Josef, Prinz, Marco

Journal:

Nature Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.11 MB

english, 2007

3

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

Endt, Kathrin, Stecher, Bärbel, Chaffron, Samuel, Slack, Emma, Tchitchek, Nicolas, Benecke, Arndt, Van Maele, Laurye, Sirard, Jean-Claude, Mueller, Andreas J., Heikenwalder, Mathias, Macpherson, Andre

Journal:

Year:

2010

Language:

english

File:

PDF, 5.45 MB

english, 2010

4

Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation

Seleznik, Gitta M, Reding, Theresia, Peter, Lukas, Gupta, Anurag, Steiner, Sabrina G, Sonda, Sabrina, Verbeke, Caroline S, Dejardin, Emmanuel, Khatkov, Igor, Segerer, Stephan, Heikenwalder, Mathias, G

Journal:

Year:

2017

Language:

english

File:

PDF, 8.24 MB

english, 2017

5

Steatohepatitis und Steatohepatitis-getriebener Leberkrebs

Heikenwälder, Mathias

Journal:

TumorDiagnostik & Therapie

Year:

2018

Language:

german

File:

PDF, 1.56 MB

german, 2018

6

Novel patient-derived preclinical models of liver cancer

Bresnahan, Erin, Ramadori, Pierluigi, Heikenwalder, Mathias, Zender, Lars, Lujambio, Amaia

Journal:

Journal of Hepatology

Year:

2020

Language:

english

File:

PDF, 992 KB

english, 2020

7

Expression of lymphotoxin beta governs immunity at two distinct levels

Tobias Junt, Alexei V. Tumanov, Nicola Harris, Mathias Heikenwalder, Nicolas Zeller, Dmitry V. Kuprash, Adriano Aguzzi, Burkhard Ludewig, Sergei A. Nedospasov, Rolf M. Zinkernagel

Journal:

European Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 810 KB

english, 2006

8

MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus

Karl S. Lang, Alexander A. Navarini, Mike Recher, Philipp A. Lang, Mathias Heikenwalder, Barbara Stecher, Andreas Bergthaler, Bernhard Odermatt, Shizuo Akira, Kenya Honda, Hans Hengartner, Rolf M. Zin

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 377 KB

english, 2007

9

Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice

Achim Weber, Regina Boger, Binje Vick, Toni Urbanik, Johannes Haybaeck, Stefan Zoller, Andreas Teufel, Peter H. Krammer, Joseph T. Opferman, Peter R. Galle, Marcus Schuchmann, Mathias Heikenwalder, He

Journal:

Year:

2010

Language:

english

File:

PDF, 2.98 MB

english, 2010

10

Prions and peripheral nerves: A deadly rendezvous

Mathias Heikenwalder, Christian Julius, Adriano Aguzzi

Journal:

Journal of Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

11

Lymphotoxin-Dependent Prion Replication in Inflammatory Stromal Cells of Granulomas

Mathias Heikenwalder, Michael O. Kurrer, Ilan Margalith, Jan Kranich, Nicolas Zeller, Johannes Haybaeck, Magdalini Polymenidou, Matthias Matter, Juliane Bremer, Walker S. Jackson, Susan Lindquist, Chr

Journal:

Year:

2008

Language:

english

File:

PDF, 2.16 MB

english, 2008

12

Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice

Johannes Attems, Arne Ittner, Kurt Jellinger, Roger M. Nitsch, Magdalena Maj, Ludwig Wagner, Jürgen Götz, Mathias Heikenwalder

Journal:

Journal of Neural Transmission

Year:

2011

Language:

english

File:

PDF, 571 KB

english, 2011

13

Prion diseases: Cannibals and garbage piles

Aguzzi, Adriano, Heikenwalder, Mathias

Journal:

Year:

2003

Language:

english

File:

PDF, 140 KB

english, 2003

14

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion

Prinz, Marco, Heikenwalder, Mathias, Junt, Tobias, Schwarz, Petra, Glatzel, Markus, Heppner, Frank L., Fu, Yang-Xin, Lipp, Martin, Aguzzi, Adriano

Journal:

Year:

2003

Language:

english

File:

PDF, 620 KB

english, 2003

15

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

Heikenwalder, Mathias, Polymenidou, Magdalini, Junt, Tobias, Sigurdson, Christina, Wagner, Hermann, Akira, Shizuo, Zinkernagel, Rolf, Aguzzi, Adriano

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 2.15 MB

english, 2004

16

Insights into prion strains and neurotoxicity

Aguzzi, Adriano, Heikenwalder, Mathias, Polymenidou, Magdalini

Journal:

Nature Reviews Molecular Cell Biology

Year:

2007

Language:

english

File:

PDF, 970 KB

english, 2007

17

Pathogenesis of prion diseases: current status and future outlook

Aguzzi, Adriano, Heikenwalder, Mathias

Journal:

Nature Reviews Microbiology

Year:

2006

Language:

english

File:

PDF, 1023 KB

english, 2006

18

Lethal recessive myelin toxicity of prion protein lacking its central domain

Baumann, Frank, Tolnay, Markus, Brabeck, Christine, Pahnke, Jens, Kloz, Ulrich, Niemann, Hartmut H, Heikenwalder, Mathias, Rülicke, Thomas, Bürkle, Alexander, Aguzzi, Adriano

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 565 KB

english, 2007

19

Prion pathogenesis in the absence of Toll-like receptor signalling

Prinz, Marco, Heikenwalder, Mathias, Schwarz, Petra, Takeda, Kiyoshi, Akira, Shizuo, Aguzzi, Adriano

Journal:

Year:

2003

Language:

english

File:

PDF, 728 KB

english, 2003

20

Current concepts and controversies in prion immunopathology

Mathias Heikenwalder, Marco Prinz, Frank L. Heppner, Adriano Aguzzi

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 346 KB

english, 2004

21

Cells and prions: A license to replicate

Mario Nuvolone, Adriano Aguzzi, Mathias Heikenwalder

Journal:

Year:

2009

Language:

english

File:

PDF, 506 KB

english, 2009

22

Germinal center B cells are dispensable in prion transport and neuroinvasion

Mathias Heikenwalder, Christian Federau, Lotta von Boehmer, Petra Schwarz, Mareike Wagner, Nicolas Zeller, Johannes Haybaeck, Marco Prinz, Burkhard Becher, Adriano Aguzzi

Journal:

Journal of Neuroimmunology

Year:

2007

Language:

english

File:

PDF, 2.58 MB

english, 2007

23

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

Andreas J. Müller, Claudia Hoffmann, Marlies Galle, Aeke Van Den Broeke, Mathias Heikenwalder, Laura Falter, Benjamin Misselwitz, Marcus Kremer, Rudi Beyaert, Wolf-Dietrich Hardt

Journal:

Cell Host & Microbe

Year:

2009

Language:

english

File:

PDF, 1.90 MB

english, 2009

24

Prions, Cytokines, and Chemokines: A Meeting in Lymphoid Organs

Adriano Aguzzi, Mathias Heikenwalder

Journal:

Year:

2005

Language:

english

File:

PDF, 290 KB

english, 2005

25

Molecular cloning, expression and regulation of the avian tubby-like protein 1 (tulp1) gene

Mathias F. Heikenwälder, Nicolás P. Koritschoner, Petr Pajer, Marie-Christine Chaboissier, Steffen M. Kurz, Karoline J. Briegel, Petr Bartunek, Martin Zenke

Journal:

Year:

2001

Language:

english

File:

PDF, 799 KB

english, 2001

26

Overexpression of Lymphotoxin in T Cells Induces Fulminant Thymic Involution

Mathias Heikenwalder, Marco Prinz, Nicolas Zeller, Karl S. Lang, Tobias Junt, Simona Rossi, Alexei Tumanov, Hauke Schmidt, Josef Priller, Lukas Flatz, Thomas Rülicke, Andrew J. Macpherson, Georg A. Ho

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 2.94 MB

english, 2008

27

P1-035: Exogenous induction of Abeta-amyloidosis: Peripheral and stainless-steel-wire inoculations

Yvonne S. Eisele, Tristan Bolmont, Mathias Heikenwalder, Zheng-Xin Yan, Klaus Roth, Adriano Aguzzi, Matthias Staufenbiel, Lary C. Walker, Mathias Jucker

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

28

Calcium binding protein Secretagogin expression in wild type and transgenic tau (P301L) mice

Johannes Attems, Magdalena Grosinger-Quass, Roger Nitsch, Magdalena Maj, Ludwig Wagner, Kurt Jellinger, Mathias Heikenwalder

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 103 KB

english, 2009

29

Various inoculation routes of Aβ-containing brain extract in APP-tg mice

Yvonne S. Eisele, Tsuyoshi Hamaguchi, Ulrike Obermueller, Goetz Heilbronner, Franziska Langer, Bruce Lamb, Matthias Staufenbiel, Mathias Heikenwalder, Mathias Jucker

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

30

Lymphotoxin, NF-?B, and Cancer: The Dark Side of Cytokines

Bauer, Judith, Namineni, Sukumar, Reisinger, Florian, Zöller, Jessica, Yuan, Detian, Heikenwälder, Mathias

Journal:

Digestive Diseases

Year:

2012

Language:

english

File:

PDF, 2.25 MB

english, 2012

31

Transfer of HBV Genomes Using Low Doses of Adenovirus Vectors Leads to Persistent Infection in Immune Competent Mice

Li–Rung Huang, Yvonne A. Gäbel, Steffi Graf, Silke Arzberger, Christian Kurts, Mathias Heikenwalder, Percy A. Knolle, Ulrike Protzer

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 2.26 MB

english, 2012

32

LINE(1)s of Evidence in HBV-Driven Liver Cancer

Heikenwalder, Mathias, Protzer, Ulrike

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 243 KB

english, 2014

33

The role of lymphotoxin signaling in the development of autoimmune pancreatitis and associated secondary extra-pancreatic pathologies

Seleznik, Gitta Maria, Zoller, Jessica, O’Connor, Tracy, Graf, Rolf, Heikenwalder, Mathias

Journal:

Cytokine & Growth Factor Reviews

Year:

2014

Language:

english

File:

PDF, 2.24 MB

english, 2014

34

Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance

Schölzel, Katrin, Schildberg, Frank A., Welz, Meike, Börner, Carolin, Geiger, Sergej, Kurts, Christian, Heikenwälder, Mathias, Knolle, Percy A., Wohlleber, Dirk

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 656 KB

english, 2014

35

Comparative effectiveness of immune-cell depletion in the treatment of autoimmune pancreatitis

Seleznik, Gitta, Reding, Theresia, Browning, Jeffrey, Segerer, Stephan, Graf, Rolf, Heikenwälder, Mathias

Journal:

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

36

The four repeat tau isoform 5 represents a calcium-dependent interaction partner of secretagogin (SCGN)

Maj, Magdalena, Wagner, Ludwig, Ilhan, Aysegul, Jellinger, Kurt, Heikenwalder, Mathias, Attems, Johannes

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

37

Lymphotoxin-associated inflammation as an etiological factor of pancreatic carcinogenesis

Seleznik, Gitta, Reding, Theresia, Sonda, Sabrina, Heikenwälder, Mathias, Graf, Rolf

Journal:

Year:

2013

Language:

english

File:

PDF, 49 KB

english, 2013

38

XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

Yabal, Monica, Müller, Nicole, Adler, Heiko, Knies, Nathalie, Groß, Christina J., Damgaard, Rune Busk, Kanegane, Hirokazu, Ringelhan, Marc, Kaufmann, Thomas, Heikenwälder, Mathias, Strasser, Andreas,

Journal:

Year:

2014

Language:

english

File:

PDF, 3.43 MB

english, 2014

39

α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets

Rothhammer, Veit, Muschaweckh, Andreas, Gasteiger, Georg, Petermann, Franziska, Heink, Sylvia, Busch, Dirk H, Heikenwälder, Mathias, Hemmer, Bernhard, Drexler, Ingo, Korn, Thomas

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 1.28 MB

english, 2014

40

Lymphotoxin promotes acinar cell reprogramming and accelerates pre-neoplastic conversion in Kras induced pancreatic tumorigenesis

Seleznik, Gitta Maria, Reding, Theresia, Sonda, Sabrina, Heikenwalder, Mathias, Graf, Rolf

Journal:

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

41

12

Borst, Katharina, Frenz, Theresa, Lienenklaus, Stefan, Köster, Mario, Namineni, Sukumar, Heikenwälder, Mathias, Sutter, Gerd, Kalinke, Ulrich

Journal:

Year:

2014

Language:

english

File:

PDF, 57 KB

english, 2014

42

The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets

Ringelhan, Marc, O'Connor, Tracy, Protzer, Ulrike, Heikenwalder, Mathias

Journal:

The Journal of Pathology

Year:

2015

Language:

english

File:

PDF, 679 KB

english, 2015

43

Direct Effects of Hepatitis B Virus-Encoded Proteins and Chronic Infection in Liver Cancer Development

Ringelhan, Marc, Heikenwalder, Mathias, Protzer, Ulrike

Journal:

Digestive Diseases

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

44

Comparative effectiveness of immune-cell depletion and a targeted therapy against LTβR-signaling in the treatment of autoimmune pancreatitis

Seleznik, Gitta Maria, Reding, Theresia, Sonda, Sabrina, Browning, Jeffrey, Segerer, Stephan, Heikenwalder, Mathias, Graf, Rolf

Journal:

Year:

2014

Language:

english

File:

PDF, 55 KB

english, 2014

45

Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo

Hösel, Marianna, Lucifora, Julie, Michler, Thomas, Holz, Gisela, Gruffaz, Marion, Stahnke, Stephanie, Zoulim, Fabien, Durantel, David, Heikenwalder, Mathias, Nierhoff, Dirk, Millet, Rachel, Salvetti,

Journal:

Year:

2014

Language:

english

File:

PDF, 856 KB

english, 2014

46

Molecular detection of hepatitis E virus (HEV) in liver biopsies after liver transplantation

Protzer, Ulrike, Böhm, Friederike, Longerich, Thomas, Seebach, Judith, Heidary Navid, Mojdeh, Friemel, Juliane, Marques-Maggio, Ewerton, Bawohl, Marion, Heikenwalder, Mathias, Schirmacher, Peter, Dutk

Journal:

Modern Pathology

Year:

2015

Language:

english

File:

PDF, 1.96 MB

english, 2015

47

Pathways of metastasizing intestinal cancer cells revealed: how will fighting metastases at the site of cancer cell arrest affect drug development?

Heikenwalder, Mathias, Borsig, Lubor

Journal:

Future Oncology

Year:

2013

Language:

english

File:

PDF, 619 KB

english, 2013

48

Tetraspanin CD63 acts as a pro-metastatic factor via β-catenin stabilization

Seubert, Bastian, Cui, Haissi, Simonavicius, Nicole, Honert, Katja, Schäfer, Sandra, Reuning, Ute, Heikenwalder, Mathias, Mari, Bernard, Krüger, Achim

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 928 KB

english, 2015

49

Bacterial Colitis Increases Susceptibility to Oral Prion Disease

Sigurdson, Christina J., Heikenwalder, Mathias, Manco, Giuseppe, Barthel, Manja, Schwarz, Petra, Stecher, Bärbel, Krautler, Nike J., Hardt, Wolf‐Dietrich, Seifert, Burkhardt, MacPherson, Andrew J. S.,

Journal:

The Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 16.78 MB

english, 2009

50

Sorafenib inhibits macrophage-induced growth of hepatoma cells by interference with insulin-like growth factor-1 secretion

Sprinzl, Martin Franz, Puschnik, Andreas, Schlitter, Anna Melissa, Schad, Arno, Ackermann, Kerstin, Esposito, Irene, Lang, Hauke, Galle, Peter Robert, Weinmann, Arndt, Heikenwälder, Mathias, Protzer,

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 1.93 MB

english, 2015